d(CH2)5Tyr(Me)AVP


SMILES COC1=CC=C(C=C1)CC2C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSC3(CCCCC3)CC(=O)N2)C(=O)N4CCCC4C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N)CC5=CC=CC=C5
InChIKey QVQOGNOOAMQKCE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 15
Hydrogen bond donors 12
Rotatable bonds 20
Molecular weight (Da) 1150.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
V1B V1BR Rat Vasopressin and oxytocin A pKi 7.42 7.42 7.42 PDSP Ki database
V1A V1AR Rat Vasopressin and oxytocin A pKi 8.75 9.12 9.48 PDSP Ki database
V2 V2R Rat Vasopressin and oxytocin A pKi 7.0 7.2 7.4 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database