Spiradoline


SMILES CN(C1CCC2(CCCO2)CC1N3CCCC3)C(=O)CC4=CC(=C(C=C4)Cl)Cl
InChIKey NYKCGQQJNVPOLU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 424.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.0 6.0 6.0 PDSP Ki database
κ OPRK Human Opioid A pKi 10.52 10.52 10.52 PDSP Ki database
μ OPRM Human Opioid A pKi 7.68 7.68 7.68 PDSP Ki database
κ OPRK Guinea pig Opioid A pKi 8.82 8.82 8.82 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database