Dermorphin


SMILES C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)NC(=O)CNC(=O)C(CC3=CC=CC=C3)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC4=CC=C(C=C4)O)N)C(=O)NC(CO)C(=O)N
InChIKey OBRCSEVKVDPXJO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 12
Hydrogen bond donors 12
Rotatable bonds 23
Molecular weight (Da) 887.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.0 6.0 6.0 PDSP Ki database
κ OPRK Human Opioid A pKi 6.0 6.0 6.0 PDSP Ki database
μ OPRM Human Opioid A pKi 9.48 9.48 9.48 PDSP Ki database
δ OPRD Rat Opioid A pKi 7.33 7.33 7.33 PDSP Ki database
μ OPRM Rat Opioid A pKi 9.34 9.34 9.34 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database