Nor-BNI


SMILES C1CC1C2CC3=C4C(=C(C=C3)O)OC5C46CCN2CC6(CC7=C5NC8=C7CC9(CN1CCC92C8OC3=C(C=CC(=C23)CC1C1CC1)O)O)O
InChIKey GYEXSFKLGQBRBJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 5
Rotatable bonds 2
Molecular weight (Da) 661.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 7.1 7.26 7.42 PDSP Ki database
δ OPRD Human Opioid A pKi 7.71 7.75 7.79 PDSP Ki database
κ OPRK Rat Opioid A pKi 6.77 8.44 9.92 PDSP Ki database
δ OPRD Mouse Opioid A pKi 7.38 7.38 7.38 PDSP Ki database
μ OPRM Rat Opioid A pKi 6.99 7.14 7.3 PDSP Ki database
κ OPRK Guinea pig Opioid A pKi 6.11 6.11 6.11 PDSP Ki database
κ OPRK Human Opioid A pKi 8.36 8.89 9.43 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database