L-366,682


SMILES CC(C=C)C(C(=O)N1CCCCC1(C=O)C(=O)N2CCCCC2)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C5CCCN5C(=O)C(CC6=CN=CN6)N
InChIKey QHUGACUEEILSLD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 5
Rotatable bonds 14
Molecular weight (Da) 755.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OT OXYR Rat Vasopressin and oxytocin A pKi 8.0 8.11 8.22 PDSP Ki database
OT OXYR Human Vasopressin and oxytocin A pKi 8.03 8.03 8.03 PDSP Ki database
V2 V2R Rat Vasopressin and oxytocin A pKi 5.51 5.62 5.74 PDSP Ki database
OT OXYR Rhesus macaque Vasopressin and oxytocin A pKi 7.77 7.77 7.77 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database