(R)-Hexbutinol


SMILES C1CCC(CC1)C(C#CCN2CCCCC2)(C3=CC=CC=C3)O
InChIKey IXXCPZGOFVCPCH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 311.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 7.58 8.13 8.68 PDSP Ki database
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.14 7.41 7.68 PDSP Ki database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 7.34 8.0 8.67 PDSP Ki database
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.71 8.12 8.52 PDSP Ki database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 7.12 7.69 8.26 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database