AF-DX 384


SMILES CCCN(CCC)CC1CCCCN1CCNC(=O)N2C3=CC=CC=C3C(=O)NC4=C2N=CC=C4.CS(=O)(=O)O
InChIKey LBXOPAJGAXATCZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 9
Molecular weight (Da) 574.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 7.51 7.51 7.51 PDSP Ki database
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.22 8.22 8.22 PDSP Ki database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 7.18 7.18 7.18 PDSP Ki database
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.0 8.0 8.0 PDSP Ki database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.27 6.27 6.27 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database