TRH


SMILES C1CC(N(C1)C(=O)C(CC2=CN=CN2)NC(=O)C3CCC(=O)N3)C(=O)N
InChIKey XNSAINXGIQZQOO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 6
Molecular weight (Da) 362.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TRH1 TRFR Human Thyrotropin-releasing hormone A pKi 7.7 7.73 7.77 PDSP Ki database
TRH1 TRHR Mouse Thyrotropin-releasing hormone A pKi 7.82 7.82 7.82 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database