N-((1s,4s)-4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)(phenyl)methanesulfonamide


SMILES CC1=CC=CC=C1N2C3=CC=CC=C3C(CC(C4=CC=CC=C42)(C)O)(C)O
InChIKey YBDIBILKFQGESG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 359.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Human Adrenoceptors A pKi 8.44 8.68 8.92 PDSP Ki database
α1B ADA1B Human Adrenoceptors A pKi 7.09 7.09 7.09 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 7.62 7.62 7.62 PDSP Ki database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.09 6.12 6.16 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database