7alpha-[(cinnamoyl)-aminomethyl]-6,14-endoethanotetrahydrothebaine


SMILES CN1CCC23C4C5(CCC2(C1CC6=C3C(=C(C=C6)OC)O4)CC5CNC(=O)C=CC7=CC=CC=C7)OC
InChIKey ZHTZIUSLOIZPHL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 500.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 7.63 7.63 7.63 PDSP Ki database
μ OPRM Human Opioid A pKi 8.77 8.77 8.77 PDSP Ki database
δ OPRD Human Opioid A pKi 7.06 7.06 7.06 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database