14beta-(2'-chlorocinnamoylamino)-7,8-dihydromorphinone


SMILES CN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)NC(=O)C=CC6=CC=CC=C6Cl
InChIKey LIARQQBYTIYDLN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 464.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 9.82 9.82 9.82 PDSP Ki database
δ OPRD Human Opioid A pKi 10.1 10.1 10.1 PDSP Ki database
κ OPRK Human Opioid A pKi 9.27 9.27 9.27 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database