1'-(o-methylcinnamoyl)-[7alpha,8alpha:3',4']-pyrrolidino-6,14-endoethenotetrahydrooripavine


SMILES CC1=CC=CC=C1C=CC(=O)N2CC3C(C2)C4(C=CC35C6CC7=C8C5(C4OC8=C(C=C7)O)CCN6C)OC
InChIKey KMRLAXVKJZMFFJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 510.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 9.66 9.66 9.66 PDSP Ki database
δ OPRD Human Opioid A pKi 8.63 8.63 8.63 PDSP Ki database
κ OPRK Human Opioid A pKi 9.28 9.28 9.28 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database