7alpha-[(cinnamyl)-aminomethyl]-6,14-endoethanotetrahydrooripavine


SMILES CN1CCC23C4C5(CCC2(C1CC6=C3C(=C(C=C6)O)O4)CC5CNCC=CC7=CC=CC=C7)OC
InChIKey XYKPUZDBFYADTM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 472.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 9.41 9.41 9.41 PDSP Ki database
δ OPRD Human Opioid A pKi 7.41 7.41 7.41 PDSP Ki database
κ OPRK Human Opioid A pKi 8.18 8.18 8.18 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database