7alpha-[(4'-chlorocinnamyl)-aminomethyl]-6,14-endoethanotetrahydrothebaine


SMILES CN1CCC23C4C5(CCC2(C1CC6=C3C(=C(C=C6)OC)O4)CC5CNCC=CC7=CC=C(C=C7)Cl)OC
InChIKey LODHFYXTHWDEIJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 520.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 7.47 7.47 7.47 PDSP Ki database
δ OPRD Human Opioid A pKi 6.13 6.13 6.13 PDSP Ki database
κ OPRK Human Opioid A pKi 7.17 7.17 7.17 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database