7alpha-[(4'-nitrocinnamoyl)-aminomethyl]-6,14-endoethanotetrahydrooripavine


SMILES CN1CCC23C4C5(CCC2(C1CC6=C3C(=C(C=C6)O)O4)CC5CNC(=O)C=CC7=CC=C(C=C7)[N+](=O)[O-])OC
InChIKey JNSXETCCDYBEEE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 531.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 9.72 9.72 9.72 PDSP Ki database
δ OPRD Human Opioid A pKi 8.27 8.27 8.27 PDSP Ki database
κ OPRK Human Opioid A pKi 8.76 8.76 8.76 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database