7alpha-[(4'-methylcinnamoyl)-aminomethyl]-6,14-endoethanotetrahydrooripavine


SMILES CC1=CC=C(C=C1)C=CC(=O)NCC2CC34CCC2(C5C36CCN(C4CC7=C6C(=C(C=C7)O)O5)C)OC
InChIKey HVJSRTWEAYGCPN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 500.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 9.64 9.64 9.64 PDSP Ki database
δ OPRD Human Opioid A pKi 8.19 8.19 8.19 PDSP Ki database
κ OPRK Human Opioid A pKi 8.51 8.51 8.51 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database