7alpha-[(4'-methoxycinnamoyl)-aminomethyl]-6,14-endoethanotetrahydrothebaine


SMILES CN1CCC23C4C5(CCC2(C1CC6=C3C(=C(C=C6)OC)O4)CC5CNC(=O)C=CC7=CC=C(C=C7)OC)OC
InChIKey ULMSSZRDKGYCJJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 530.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 7.89 7.89 7.89 PDSP Ki database
δ OPRD Human Opioid A pKi 6.49 6.49 6.49 PDSP Ki database
κ OPRK Human Opioid A pKi 6.96 6.96 6.96 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database