7alpha-[(4'-Methylcinnamoyl)-aminomethyl]-6,14-endoethanotetrahydrothebaine


SMILES CC1=CC=C(C=C1)C=CC(=O)NCC2CC34CCC2(C5C36CCN(C4CC7=C6C(=C(C=C7)OC)O5)C)OC
InChIKey FLLNTYIXKCHHQH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 514.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 7.93 7.93 7.93 PDSP Ki database
δ OPRD Human Opioid A pKi 6.61 6.61 6.61 PDSP Ki database
κ OPRK Human Opioid A pKi 6.8 6.8 6.8 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database