3-((3R,4R)-1-((S)-3-cyclohexyl-3-hydroxypropyl)-3,4-dimethylpiperidin-4-yl)phenol


SMILES CC1CN(CCC1(C)C2=CC(=CC=C2)O)CCC(C3CCCCC3)O
InChIKey LVVHEFJXPXAUDD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 345.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 9.82 10.0 10.37 PDSP Ki database
δ OPRD Human Opioid A pKi 8.32 8.52 8.92 PDSP Ki database
κ OPRK Human Opioid A pKi 8.33 8.72 9.49 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database