Yohimbine Hydrochloride


SMILES COC(=O)C1C(CCC2C1CC3C4=C(CCN3C2)C5=CC=CC=C5N4)O.Cl
InChIKey PIPZGJSEDRMUAW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 390.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pKi 8.74 8.74 8.74 PDSP Ki database
α2B ADA2B Human Adrenoceptors A pKi 7.82 7.82 7.82 PDSP Ki database
α2C ADA2C Human Adrenoceptors A pKi 8.72 8.72 8.72 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database