nalmefene


SMILES C=C1CCC2(C3CC4=C5C2(C1OC5=C(C=C4)O)CCN3CC6CC6)O
InChIKey WJBLNOPPDWQMCH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 339.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.88 7.93 8.03 PDSP Ki database
κ OPRK Human Opioid A pKi 8.99 9.3 9.92 PDSP Ki database
μ OPRM Human Opioid A pKi 9.04 9.15 9.36 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database