(S)-2-((S)-2-(((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)methyl)-3-phenylpropanamido)-4-phenylbutanoic acid


SMILES CC1CN(CCC1(C)C2=CC(=CC=C2)O)CC(CC3=CC=CC=C3)C(=O)NC(CCC4=CC=CC=C4)C(=O)O
InChIKey VXOIRRPDOYHHNF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 11
Molecular weight (Da) 528.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 8.33 8.33 8.33 PDSP Ki database
δ OPRD Human Opioid A pKi 8.0 8.0 8.0 PDSP Ki database
κ OPRK Human Opioid A pKi 6.29 6.29 6.29 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database