(S)-2-(biphenyl-4-ylmethyl-{3-[(3R,4R)-4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-yl]-propionyl}-amino)-3-phenyl-propionic acid


SMILES CC1CN(CCC1(C)C2=CC(=CC=C2)O)CCC(=O)N(CC3=CC=C(C=C3)C4=CC=CC=C4)C(CC5=CC=CC=C5)C(=O)O
InChIKey QIDWLHXLGKPNAX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 11
Molecular weight (Da) 590.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 6.64 6.64 6.64 PDSP Ki database
μ OPRM Human Opioid A pKi 7.13 7.13 7.13 PDSP Ki database
δ OPRD Human Opioid A pKi 7.28 7.28 7.28 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database