(S)-2-(3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)-4-phenylbutanoic acid


SMILES CC1CN(CCC1(C)C2=CC(=CC=C2)O)CCC(=O)NC(CCC3=CC=CC=C3)C(=O)O
InChIKey YJYUIXQWAGWQFA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 9
Molecular weight (Da) 438.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.44 6.44 6.44 PDSP Ki database
κ OPRK Human Opioid A pKi 6.16 6.16 6.16 PDSP Ki database
μ OPRM Human Opioid A pKi 7.24 7.24 7.24 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database