(S)-3-biphenyl-4-yl-2-{3-[(3R,4R)-4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-yl]-propionylamino}-propionic acid


SMILES CC1CN(CCC1(C)C2=CC(=CC=C2)O)CCC(=O)NC(CC3=CC=C(C=C3)C4=CC=CC=C4)C(=O)O
InChIKey KSBKSXFVNXPLNA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 9
Molecular weight (Da) 500.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 7.1 7.1 7.1 PDSP Ki database
δ OPRD Human Opioid A pKi 6.8 6.8 6.8 PDSP Ki database
κ OPRK Human Opioid A pKi 5.96 5.96 5.96 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database