17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5r-epoxy-6beta-[(3'-quinolyl)acetamido]morphinan


SMILES C1CC1CN2CCC34C5C(CCC3(C2CC6=C4C(=C(C=C6)O)O5)O)NC(=O)C7=CC8=CC=CC=C8N=C7
InChIKey JPHBARUGZJTJNG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 4
Molecular weight (Da) 497.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.49 7.71 7.94 PDSP Ki database
κ OPRK Human Opioid A pKi 8.74 8.99 9.24 PDSP Ki database
μ OPRM Human Opioid A pKi 9.92 10.04 10.15 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database