17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5r-epoxy-6beta-[(4'-pyridyl)acetamido]morphinan


SMILES C1CC1CN2CCC34C5C(CCC3(C2CC6=C4C(=C(C=C6)O)O5)O)NC(=O)C7=CC=NC=C7
InChIKey XQWZTPWKACKUMJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 4
Molecular weight (Da) 447.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.56 6.64 6.73 PDSP Ki database
κ OPRK Human Opioid A pKi 7.22 7.46 7.71 PDSP Ki database
μ OPRM Human Opioid A pKi 9.32 9.38 9.43 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database