endo-8-(1H-Indol-3-ylmethyl)-3-(4-chlorophenyl)-8-azabicyclo-[3.2.1]octan-3-ol


SMILES C1CC2CC(CC1N2CC3=CNC4=CC=CC=C43)(C5=CC=C(C=C5)Cl)O
InChIKey AXPWNFAVTPIWHV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 366.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 6.8 6.8 6.8 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 7.6 7.6 7.6 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 5.52 5.52 5.52 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database