N-Cyclopropylmethyl-14beta-cinnamoyloxy-7,8-dihydrocodeinone


SMILES COC1=C2C3=C(CC4C5(C3(CCN4CC6CC6)C(O2)C(=O)CC5)OC(=O)C=CC7=CC=CC=C7)C=C1
InChIKey WGDLNMCFJZEUHA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 485.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.74 6.74 6.74 PDSP Ki database
κ OPRK Human Opioid A pKi 8.37 8.37 8.37 PDSP Ki database
μ OPRM Human Opioid A pKi 8.6 8.6 8.6 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database