3-desoxy-3-carboxamidonaltrexone


SMILES C1CC1CN2CCC34C5C(=O)CCC3(C2CC6=C4C(=C(C=C6)C(=O)N)O5)O
InChIKey QAICPHMNUHNDMC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 368.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 9.15 9.15 9.15 PDSP Ki database
δ OPRD Human Opioid A pKi 6.26 6.26 6.26 PDSP Ki database
κ OPRK Human Opioid A pKi 7.96 8.7 9.44 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database