(1R,13S,14R)-24-(cyclopropylmethyl)-13,20-dihydroxy-4,24-diazahexacyclo[12.7.3.0^{1,13}.0^{3,11}.0^{5,10}.0^{16,21}]tetracosa-3(11),5(10),6,8,16(21),17,19-heptaene-19-carboxamide


SMILES C1CC1CN2CCC34CC5=C(CC3(C2CC6=C4C(=C(C=C6)C(=O)N)O)O)C7=CC=CC=C7N5
InChIKey SYDFANRJNFCVKV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 3
Molecular weight (Da) 443.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 9.09 9.09 9.09 PDSP Ki database
μ OPRM Human Opioid A pKi 9.29 9.29 9.29 PDSP Ki database
δ OPRD Human Opioid A pKi 10.6 10.6 10.6 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database