(1S,9R,10S)-17-(cyclopropylmethyl)-3,10-dihydroxy-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-triene-4-carboxamide


SMILES C1CCC2(C3CC4=C(C2(C1)CCN3CC5CC5)C(=C(C=C4)C(=O)N)O)O
InChIKey XMMYBZHHAZNWDZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 3
Molecular weight (Da) 356.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.38 8.38 8.38 PDSP Ki database
μ OPRM Human Opioid A pKi 9.8 9.8 9.8 PDSP Ki database
κ OPRK Human Opioid A pKi 9.54 9.54 9.54 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database