(1R,9R,10S,13R)-17-(cyclobutylmethyl)-3,10,13-trihydroxy-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-triene-4-carboxamide


SMILES C1CC(C1)CN2CCC34CC(CCC3(C2CC5=C4C(=C(C=C5)C(=O)N)O)O)O
InChIKey NWIALXFYKPFWTR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 3
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.11 7.76 8.41 PDSP Ki database
κ OPRK Human Opioid A pKi 8.05 8.76 9.47 PDSP Ki database
μ OPRM Human Opioid A pKi 9.28 9.71 10.14 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database