4aR,9aS,2'R-(+)-cis-2-(2'-Hydroxy-2'-phenylethyl)-4a-ethyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ol


SMILES CCC12CCN(CC1OC3=C2C=C(C=C3)O)CC(C4=CC=CC=C4)O
InChIKey IWQGUHXUWMPTNL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 339.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 5.88 6.81 8.03 PDSP Ki database
δ OPRD Human Opioid A pKi 5.51 5.89 6.35 PDSP Ki database
κ OPRK Human Opioid A pKi 5.02 5.65 6.38 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database