(-)-trans-9-Methoxy-3-(2-phenylethyl)-2,3,4,4aalpha,5,6,7,7aalpha-octahydro-1H-benzo[4,5]furo[3,2-e]isoquinoline


SMILES COC1=CC=CC2=C1OC3C24CCN(CC4CCC3)CCC5=CC=CC=C5
InChIKey HVQROFSHEXGBAM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 363.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 5.73 5.84 5.94 PDSP Ki database
δ OPRD Human Opioid A pKi 5.08 5.7 6.31 PDSP Ki database
μ OPRM Human Opioid A pKi 6.84 7.23 7.62 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database