7-((1R,4R)-5-((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-yl)methyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)benzo[d]oxazol-2(3H)-one


SMILES C1CC2=C(CC1CN3CC4CC3CN4C5=CC=CC6=C5OC(=O)N6)C7=C(N2)C=CC(=C7)F
InChIKey JDKQOFWWKCLDDD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 432.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.74 5.74 5.74 PDSP Ki database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.78 6.78 6.78 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 7.85 7.88 7.92 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database