(+)-1-{(1S,2S,5R)-8-[2-(3,4-Dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonan-8-yl}propan-1-one


SMILES CCC(=O)N1CC2C(CCC1CN2C(=O)CC3=CC(=C(C=C3)Cl)Cl)N4CCCC4
InChIKey OVUUJSWTQQWBBJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 437.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.0 6.0 6.0 PDSP Ki database
κ OPRK Human Opioid A pKi 6.0 6.23 6.92 PDSP Ki database
μ OPRM Human Opioid A pKi 6.0 6.05 6.19 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database