(1R,2R,5S)-methyl 8-(2-(3,4-dichlorophenyl)acetyl)-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonane-6-carboxylate


SMILES COC(=O)N1CC2C(CCC1CN2C(=O)CC3=CC(=C(C=C3)Cl)Cl)N4CCCC4
InChIKey OMVSGZSRXSCVQR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 439.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.0 6.0 6.0 PDSP Ki database
κ OPRK Human Opioid A pKi 6.0 6.57 8.22 PDSP Ki database
μ OPRM Human Opioid A pKi 5.21 6.02 6.85 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database