(-)-1-[(1R,2S,5S)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8-diazabicyclo-[3.2.2]nonan-8-yl]-2-(3,4-dichlorophenyl)ethanone


SMILES C1CCN(C1)C2CCC3CN(C2CN3CC4=CC=CC=C4)C(=O)CC5=CC(=C(C=C5)Cl)Cl
InChIKey PTOAIOGDLYUSHV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 471.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 5.82 6.25 7.15 PDSP Ki database
μ OPRM Human Opioid A pKi 5.94 6.25 6.74 PDSP Ki database
δ OPRD Human Opioid A pKi 6.0 6.0 6.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database