abediterol


SMILES O=c1ccc2c([nH]1)c(O)ccc2[C@H](CNCCCCCCOCC(c1ccccc1)(F)F)O
InChIKey SFYAXIFVXBKRPK-QFIPXVFZSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 13
Molecular weight (Da) 460.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Human Adrenoceptors A pIC50 7.44 7.44 7.44 Guide to Pharmacology
β2 ADRB2 Human Adrenoceptors A pIC50 9.22 9.22 9.22 Guide to Pharmacology
β3 ADRB3 Human Adrenoceptors A pIC50 5.52 5.52 5.52 Guide to Pharmacology
β1 ADRB1 Human Adrenoceptors A pEC50 7.44 7.44 7.44 ChEMBL
β2 ADRB2 Human Adrenoceptors A pEC50 8.72 8.97 9.22 ChEMBL