17-phenyl-ω-trinor-PGE2


SMILES OC(=O)CCC/C=C\C[C@H]1C(=O)C[C@H]([C@@H]1/C=C/[C@H](CCc1ccccc1)O)O
InChIKey FOBVMYJQWZOGGJ-XYRJXBATSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 11
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP1 PE2R1 Human Prostanoid A pKi 8.1 8.1 8.1 Guide to Pharmacology
EP1 PE2R1 Mouse Prostanoid A pKi 7.9 7.9 7.9 Guide to Pharmacology
EP3 PE2R3 Rat Prostanoid A pKi 8.37 8.37 8.37 Guide to Pharmacology
EP3 PE2R3 Mouse Prostanoid A pKi 8.43 8.43 8.43 Guide to Pharmacology
EP1 PE2R1 Rat Prostanoid A pKi 7.6 7.6 7.6 Guide to Pharmacology
EP2 PE2R2 Rat Prostanoid A pKi 6.1 6.1 6.1 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database