NF-56-EJ40


SMILES CN1CCN(CC1)Cc1ccc(cc1)c1cccc(c1)C(=O)Nc1ccccc1CC(=O)O
InChIKey UTWXDNZWMQAUKL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 443.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Structure pdb 6RNK

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
succinate SUCR1 Human Succinate A pKi 7.76 7.76 7.76 Guide to Pharmacology
succinate SUCR1 Human Succinate A pKd 7.48 7.48 7.48 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
succinate SUCR1 Human Succinate A pIC50 7.6 7.6 7.6 ChEMBL