ArrestinDb

noradrenaline

SMILES	NCC(c1ccc(c(c1)O)O)O
InChIKey	SFLSHLFXELFNJZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors	4
Hydrogen bond donors	4
Rotatable bonds	2
Molecular weight (Da)	169.1

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Endogenous
Approved drug	No

Database connections

Guide To Pharmacology ChEMBL_compound_ids PubChem GPCRdb
Ligand site mutations	β₁ β₂

Search:

Receptor					Activity				Source
GTP No matches found	Uniprot No matches found	Species No matches found	Family No matches found	Class No matches found	Type No matches found	Min	Avg	Max	Database No matches found
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pKi	5.0	5.42	6.26	PDSP Ki database
5-HT_1B	5HT1B	Rat	5-Hydroxytryptamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
5-HT_2A	5HT2A	Rat	5-Hydroxytryptamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
5-HT_2A	5HT2A	Bovine	5-Hydroxytryptamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
5-HT_2C	5HT2C	Rat	5-Hydroxytryptamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
5-HT_5A	5HT5A	Rat	5-Hydroxytryptamine	A	pKi	5.0	5.5	6.0	PDSP Ki database
5-HT_5A	5HT5A	Mouse	5-Hydroxytryptamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
5-HT₆	5HT6R	Mouse	5-Hydroxytryptamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
5-HT₇	5HT7R	Human	5-Hydroxytryptamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
5-HT₇	5HT7R	Rat	5-Hydroxytryptamine	A	pKi	6.0	6.09	6.26	PDSP Ki database
CB₁	CNR1	Human	Cannabinoid	A	pKi	6.0	6.0	6.0	PDSP Ki database
D₁	DRD1	Human	Dopamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
D₁	DRD1	Human	Dopamine	A	pKi	4.3	4.3	4.3	Guide to Pharmacology
D₁	DRD1	Bovine	Dopamine	A	pKi	6.09	6.39	6.7	PDSP Ki database
D₁	DRD1	Rat	Dopamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
D₂	DRD2	Rat	Dopamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
D₂	DRD2	Human	Dopamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
D₂	DRD2	Bovine	Dopamine	A	pKi	5.0	5.12	5.25	PDSP Ki database
D₂	DRD2	Dog	Dopamine	A	pKi	5.22	5.22	5.22	PDSP Ki database
D₅	DRD5	Human	Dopamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
D₅	DRD5	Human	Dopamine	A	pKi	4.9	4.9	4.9	Guide to Pharmacology
TA₁	TAAR1	Human	Trace amine	A	pKi	5.0	5.0	5.0	PDSP Ki database
α_1A	Q9TSW7	Pig	Adrenoceptors	A	pKi	5.0	5.12	5.3	PDSP Ki database
α_1B	ADA1B	Human	Adrenoceptors	A	pKi	5.0	5.39	6.04	PDSP Ki database
α_1B	ADA1B	Rat	Adrenoceptors	A	pKi	5.0	5.0	5.0	PDSP Ki database
α_1B	A0A4X1U0M4	Pig	Adrenoceptors	A	pKi	5.6	5.6	5.6	PDSP Ki database
α_1D	ADA1D	Human	Adrenoceptors	A	pKi	5.0	5.03	5.06	PDSP Ki database
α_2A	ADA2A	Human	Adrenoceptors	A	pKi	5.7	6.03	6.4	PDSP Ki database
α_2A	ADA2A	Pig	Adrenoceptors	A	pKi	5.25	5.84	6.43	PDSP Ki database
α_2A	ADA2A	Mouse	Adrenoceptors	A	pKi	5.85	5.85	5.85	PDSP Ki database
α_2B	ADA2B	Human	Adrenoceptors	A	pKi	5.56	6.02	6.48	PDSP Ki database
α_2C	ADA2C	Human	Adrenoceptors	A	pKi	5.87	6.05	6.23	PDSP Ki database
β₁	ADRB1	Human	Adrenoceptors	A	pKi	5.45	5.45	5.45	PDSP Ki database
β₁	ADRB1	Human	Adrenoceptors	A	pKi	6.0	6.0	6.0	Guide to Pharmacology
β₂	ADRB2	Human	Adrenoceptors	A	pKi	5.0	5.27	6.1	PDSP Ki database
β₂	ADRB2	Human	Adrenoceptors	A	pKi	5.4	5.4	5.4	Guide to Pharmacology
β₃	ADRB3	Human	Adrenoceptors	A	pKi	5.37	5.37	5.37	PDSP Ki database

Showing 1 to 39 of 39 entries

Search:

Receptor					Activity				Source
GTP No matches found	Uniprot No matches found	Species No matches found	Family No matches found	Class No matches found	Type No matches found	Min	Avg	Max	Database No matches found
TA₁	TAAR1	Human	Trace amine	A	pEC50	4.91	4.91	4.91	ChEMBL

Showing 1 to 1 of 1 entries

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Main reference

noradrenaline

Chemical properties

Drug properties

Database connections

Bioactivities