N-palmitoylethanolamine


SMILES CCCCCCCCCCCCCCCC(=O)NCCO
InChIKey HXYVTAGFYLMHSO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 16
Molecular weight (Da) 299.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Endogenous
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pKi 8.28 8.28 8.28 Drug Central
CB1 CNR1 Human Cannabinoid A pKi 5.3 5.3 5.3 PDSP Ki database
CB2 CNR2 Human Cannabinoid A pKi 8.28 8.28 8.28 Drug Central
CB2 CNR2 Human Cannabinoid A pKi 5.3 5.3 5.3 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR55 GPR55 Human GPR18, GPR55 and GPR119 A pEC50 8.08 8.08 8.08 Drug Central
GPR55 GPR55 Human GPR18, GPR55 and GPR119 A pEC50 8.4 8.4 8.4 Guide to Pharmacology
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 7.05 7.05 7.05 ChEMBL