PF-6870961


SMILES CC1=CN2C=C(CC(=O)N3CCC4(CN(C4)[C@@H]5CCC6=CC(=CC=C56)C7=CC(C)=NC(O)=N7)CC3)N=C2S1
InChIKey QVWZNQBFKUFFHO-RUZDIDTESA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 528.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ghrelin GHSR Human Ghrelin A pKi 7.13 7.13 7.13 Guide to Pharmacology
ghrelin GHSR Rat Ghrelin A pKi 6.62 6.62 6.62 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database