D-tryptophan


SMILES OC(=O)[C@@H](Cc1c[nH]c2c1cccc2)N
InChIKey QIVBCDIJIAJPQS-SECBINFHSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 3
Rotatable bonds 3
Molecular weight (Da) 204.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Endogenous
Approved drug Yes

Database connections

Structure pdb 7DD5 7DD6 9C1P 8WPG 8SZF 8SZG 8SZI 8SZH 8WPU 8SZI 7DD7 7DTU 7DTV 7M3E 7M3F 7M3G 9C2F

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CaS CASR Human Calcium-sensing C pKd 2.6 3.5 4.4 Guide to Pharmacology
GPR139 GP139 Human Orphan A pKi 3.13 3.13 3.13 Guide to Pharmacology
CaS CASR Human Calcium-sensing C pKd 8.36 8.36 8.36 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR139 GP139 Human Orphan A pIC50 4.59 4.59 4.59 Guide to Pharmacology
GPR139 GP139 Human Orphan A pEC50 3.66 3.66 3.66 Guide to Pharmacology
TSH TSHR Human Glycoprotein hormone A Potency 4.4 4.4 4.4 ChEMBL
GPR139 GP139 Human Orphan A pIC50 8.34 8.34 8.34 Drug Central
HCA3 HCAR3 Human Hydroxycarboxylic acid A pEC50 5.01 5.01 5.01 Guide to Pharmacology