RBI257


SMILES CC(Oc1cccnc1N(C1CCN(CC1)Cc1ccc(cc1)I)C)C
InChIKey ZJAXDNQQFMPNAV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 465.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 9.48 9.48 9.48 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.55 5.55 5.55 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.84 6.84 6.84 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.56 6.56 6.56 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.25 6.25 6.25 ChEMBL
D4 DRD4 Rat Dopamine A pKi 9.6 9.6 9.6 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database