RO5101576


SMILES OC(=O)CCc1c(CCCCCCOc2cc(cc(c2)c2ccc3c(c2)OCO3)c2ccsc2)cccc1OCCCC(=O)O
InChIKey SRPFDFNVILUDAI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 18
Molecular weight (Da) 630.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
BLT1 LT4R1 Human Leukotriene A pIC50 8.1 8.1 8.1 Guide to Pharmacology
BLT2 LT4R2 Human Leukotriene A pIC50 6.79 6.79 6.79 ChEMBL
BLT1 LT4R1 Human Leukotriene A pIC50 6.94 8.15 9.36 ChEMBL