CHEMBL142217


SMILES N#Cc1ccc2[nH]cc(CN3CCN(c4ccccc4)CC3)c2c1
InChIKey VHPASGHENHNLAW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 316.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.52 5.52 5.52 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.3 7.3 7.3 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.36 5.36 5.36 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.47 4.96 5.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database