almotriptan


SMILES CN(CCc1c[nH]c2c1cc(cc2)CS(=O)(=O)N1CCCC1)C
InChIKey WKEMJKQOLOHJLZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 335.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 8.1 8.1 8.1 Drug Central
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.12 8.12 8.12 Drug Central
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 8.14 8.14 8.14 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pIC50 7.92 7.92 7.92 Guide to Pharmacology
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pIC50 7.89 7.89 7.89 Guide to Pharmacology